MSC’s are undifferentiated cells that are naturally available in your body. They have the capability to send out signals to growth factors and proteins that reduce inflammation and promote healing. They even stimulate your own innate stem cells and proliferate healthy cells to ultimately reduce pain, repair tissue, and improve function.
MSC’s represent an evolution in treating musculoskeletal injuries and neurological conditions. They are a breakthrough, non-surgical treatment option for individuals suffering from low back pain, joint pain, other soft tissue injuries, and neurological conditions. MSC’s have great potential to actually accelerate the healing of injuries in a better, more complete way.
ExTracellular Vesicles:
Extracellular Vesicles are small packages of information that are isolated vesicles from mesenchymal stem cells (MSC’s). They act locally to exert a biologic effect. They contain proteins, messenger-RNA and micro-RNA that have anti-inflammatory benefits, inhibit cell death, increase blood flow.
What is Mesenchymal Cell Therapy?
MSC’s are undifferentiated cells that are naturally stored and available in your body. They have the ability to send out signals, growth factors, and proteins that helped to reduce inflammation and promote healing on a cellular level. They can be harvested from a person’s bone marrow or adipose tissue.
Mesenchymal Cell Therapy Reviews
How do Mesenchymal Cells work?
Stem cells may function to aid in stimulating injured tissue to repair back to healthy tissue. A release proteins, growth factors that function to reduce inflammation, increased blood flow, restore a healthy environment and allow restoration of a healthy micro-environment.
Most common treated conditions?
- Joint pain secondary to osteoarthritis (knee, shoulder, hip, facet joints)
- Soft tissue injuries (muscle and tendon tears)
- Low back pain caused by a painful disc with internal disc disruption (tears) and/or degenerative disc disease
- They are also being used to treat some neurological and autoimmune conditions
What are the sources of the Mesenchymal stem cells used?
Three known reliable sources of stem cells can be used in treatment. Two sources are taken from your own body (autologous), bone marrow (usually your hip bone), or adipose tissue (usually abdominal fat). The third reliable source of stem cells is derived from a source other than your own body (allogeneic) - a newborn’s umbilical cord tissue and blood donated from a healthy mother and baby.
Autologous stem cells from bone marrow concentrate – Bone marrow-derived stem mesenchymal stem cells can be safely and easily taken from the hip bone and then concentrated through a specialized process performed on-site the same day. When handled and injected carefully and correctly, stem cells help set up a healthy environment and stimulate a regenerative process to create healthy tissue and repair injuries.
Autologous stem cells from adipose tissue concentrate. The center is currently using a novel autologous concentrating system from Lipogems – This system uses the patient’s own adipose tissue taken from superficial abdominal fat. It is concentrated at the bedside using mechanical methods (vs using chemicals like collagenase that the FDA has objected to using for safety issues). This helps to isolate and concentrate the useful stem cells and growth factors that are plentiful in adipose tissue. This is a same-day procedure that can be performed in our state-of-the-art surgery center. With the use of conscious sedation patients usually, experience only minimal discomfort. Adipose-derived stem cells and growth factors have proven to be very effective for treating painful OA in joints like the knee.
Stem cells derived from a newborn's umbilical cord blood and tissue (Wharton’s jelly) have high concentrations of healthy young stem cells and are a rich source of proteins and growth factors. They have proven to be safe, effective and produce a profound effect in stimulating a healing and regenerative process for injuries and degenerative conditions. This is a powerful option, given that the stem cells of a newborn are healthy, potent, and plentiful. This product is donated from a healthy mother and child. It is tested several times to ensure they are safe for use (healthy and disease-free). There is essentially no chance of rejection or adverse reaction. Umbilical cord stem cells should not be confused with fetal stem cells - they do not have the ethical, legal, or safety issues that are associated with fetal-derived stem cells.
Mesenchymal Cell Therapy FAQs
What can Mesenchymal Cell Therapy help?
Because MSCs utilize a cell-based science to treat ailments, they are a highly versatile form of treatment. In orthopedic specialties, they are a great tool for treating a range of joint, tissue, and neurological concerns. At Southwest Spine & Sports, we tend to recommend MSCs for patients who suffer from arthritis, chronic pain, or muscle/tendon tears that resist healing with rest and ice.
How effective is this treatment?
With any newer treatment types, patients often understandably wonder about their efficacy. Some stem cell therapies have been shown to be up to 80% effective. The exact results can vary on many factors, so please don't hesitate to bring this question up in your consultation appointment at our Scottsdale, AZ practice.
Is it ethical to get Mesenchymal Cell Therapy?
As a newer treatment on the market, cell therapies have come under question as to their validity. As technology has advanced, we are now able to harvest stem cells from a multitude of viable sources that are both ethical and often autologous, or in other words, come from the same individual whom they are treating. For more information on where various stem cells originate, please see our section on this webpage dedicated to the various sources.
